IPDMA Critical Appraisal Checklist

Individual Participant Data Meta-analysis (IPDMA) is the gold standard for evidence synthesis! Here is the resaerch protocol: The Research Protocol.

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The scope of the critical appraisal tool:

• Research question
• Developing and registration of protocol and SAP
• Access to data
• Data prepartion and harmonization
• Appropriateness of handling non-availability of IPD
• Appropriateness of data analysis (overall)
• Appropriateness of data analysis (Interaction effect)
• Missing data
• Heterogeneity
• Interpretation
• Reporting
• Special consideratiion for observational studies

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